WHY BRYHALI LOTION?

Unique topical treatment

BRYHALI Lotion is a low-concentration formulation designed to limit your exposure to the negative side effects of steroids. BRYHALI Lotion helps relieve itching, inflammation, plaque buildup, flaking, and dryness in the places affected by psoriasis.

Local adverse reactions from topical corticosteroids may include thinning of skin (atrophy), stretch marks (striae), spider veins (telangiectasia), lightened skin (hypopigmentation) and rash (allergic contact dermatitis). Some local adverse reactions may be irreversible.

You can use it for up to 8 weeks

Thanks to a lower concentration of the active steroid ingredient, BRYHALI Lotion has safety proven for up to 8 weeks of use.

Continued results 4 weeks post treatment

In 2 clinical trials, BRYHALI Lotion continued to provide relief from psoriasis even 4 weeks after patients stopped using it.

It’s convenient and applies easily

That’s because you only have to apply it once a day, and its lotion technology contains moisturizers. You may also use moisturizers as needed.

No increased skin thinning

In 2 clinical trials each lasting 8 weeks, there were no patients who had thinning of the skin related to treatment with BRYHALI Lotion.

Local adverse reactions from topical corticosteroids may include thinning of skin (atrophy), stretch marks (striae), spider veins (telangiectasia), lightened skin (hypopigmentation) and rash (allergic contact dermatitis). Some local adverse reactions may be irreversible. Tell your doctor if you get any skin reactions or skin infections.

In a satisfaction survey, 100% of patients said they strongly or somewhat agreed that BRYHALI Lotion vehicle:
  • ABSORBED QUICKLY
  • DID NOT LEAVE SKIN FEELING GREASY
  • FELT LIGHT ON THE SKIN
  • LEFT SKIN FEELING MOISTURIZED FOR 24 HOURS

BENEFITS OF BRYHALI LOTION

In clinical studies BRYHALI Lotion relieved the symptoms of psoriasis
  • Inflammation
  • Plaque buildup
  • Scaling
  • In 2 clinical studies, efficacy was based primarily on results of the Investigator’s Global Assessment (IGA). In addition to the IGA, clinical studies included evaluations of improvement in the signs of psoriasis (inflammation, plaque buildup, and scaling).
  • 37% and 38% of patients using BRYHALI Lotion achieved treatment success (meaning they were clear or almost clear) at week 8, compared to 8% and 12% of patients who used the vehicle lotion.
And also reduced local skin reactions
  • Irritation
  • Itching
  • Dryness
  • In 2 clinical studies, tolerability of BRYHALI Lotion was evaluated through a special safety assessment of selected local signs and symptoms of psoriasis, including the severity of itching, dryness, and burning/stinging.
  • By week 2, reductions in severe local skin reactions were seen from baseline vs vehicle; itching (83% vs 22%), irritation (78% vs 0%), and dryness (74% vs 34%).
  • The most common side effects of BRYHALI Lotion include burning, stinging, itching, dryness (application site dermatitis), upper respiratory tract infection, and high blood sugar (hypoglycemia).
In clinical studies
ZERO CASES
OF SKIN THINNING

NO INCREASED SKIN THINNING RELATED TO TREATMENT WITH BRYHALI LOTION

Local adverse reactions from topical corticosteroids may include thinning of skin (atrophy), stretch marks (striae), spider veins (telangiectasia), lightened skin (hypopigmentation) and rash (allergic contact dermatitis). Some local adverse reactions may be irreversible.

Your healthcare provider may tell you to stop using BRYHALI Lotion until your skin heals, or your healthcare provider may tell you to use it less often if you get too much skin irritation.

In 2 clinical studies of patients with moderate-to-severe plaque psoriasis.

USING BRYHALI LOTION

BRYHALI Lotion is easy to use

Simply apply a thin layer to the affected area once a day and rub in gently. Avoid using on the face, groin, and armpit areas, or wrapping, bandaging, or blocking the treated surface. Your total dosage should not exceed 50 grams per week.

See Important Safety Information for BRYHALI Lotion below.

BEFORE AND AFTER

What skin clearance could look like for you

43-year-old female
After
Before

These photos represent actual clinical experience. Photos have not been retouched. Individual results may vary.

45-year-old female
After
Before

These photos represent actual clinical experience. Photos have not been retouched. Individual results may vary.

40-year-old male
After
Before

These photos represent actual clinical experience. Photos have not been retouched. Individual results may vary.

Patients applied BRYHALI Lotion to affected areas once a day for 8 weeks. Individual results may vary.

FREQUENTLY ASKED QUESTIONS

GENERAL
What is BRYHALI Lotion?

BRYHALI is a prescription corticosteroid medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if BRYHALI is safe and effective in children under 18 years of age.

What should I tell my doctor before using BRYHALI Lotion?

Before using BRYHALI Lotion, tell your doctor about all your medical conditions, including if you:

  • Have had irritation or other skin reactions to a steroid medicine in the past
  • Have a skin infection
  • Have diabetes
  • Have adrenal gland problems
  • Have liver problems
  • Are pregnant or plan on becoming pregnant
  • Are breastfeeding or plan to breastfeed

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take other corticosteroids medicines by mouth, or injection, or use other products on your skin that contain corticosteroids.

How does BRYHALI Lotion work?

The active ingredient in BRYHALI Lotion is halobetasol, a corticosteroid designed to reduce irritation, inflammation, itching, plaque buildup, scaling, and dryness in areas affected by plaque psoriasis.

Where on my body can I use BRYHALI Lotion?

Do not apply BRYHALI Lotion in your mouth, eyes, or vagina. Additionally, avoid applying BRYHALI Lotion to your face, groin, and armpit area. If you are breastfeeding, do not apply BRYHALI Lotion to your nipple or areola.

Can I use a moisturizer with BRYHALI Lotion?

Yes, you can use additional moisturizers as frequently as you want. BRYHALI Lotion is also uniquely designed to contain moisturizers within the lotion itself.

What’s the difference between topicals and other treatments?

One of the main differences between treatments is the way they are applied. Topicals are applied directly to the affected area and are usually creams or ointments. Other treatments may involve injection or a pill taken orally.

How well does BRYHALI Lotion work?

In clinical trials, a significant number of BRYHALI Lotion patients had clear to almost clear skin (treatment success) after 8 weeks of use. There were also a substantial number of patients who had improved relief from inflammation, plaque buildup, and flaking. 37% and 38% of patients using BRYHALI Lotion achieved treatment success at week 8, compared to 8% and 12% of patients who used the vehicle lotion.

SAFETY
Can I use BRYHALI Lotion if I am pregnant or breastfeeding?

Consult your doctor if you are pregnant or trying to get pregnant and want to see if BRYHALI Lotion is right for you. If you are breastfeeding and your doctor prescribes BRYHALI Lotion, do not apply BRYHALI Lotion to your nipple or areola.

What are the most common side effects I should know about?

The most common side effects of BRYHALI Lotion are burning, stinging, itching, dryness (application site dermatitis), upper respiratory tract infection and high blood sugar (hyperglycemia).

If you experience any of these side effects, stop using BRYHALI Lotion and consult your doctor.

What other safety information do I need to know?

BRYHALI Lotion may cause more serious effects, including:

  • Causing your adrenal glands to stop working
  • Cushing’s syndrome, a condition that happens when your body is exposed to too much of a hormone called cortisol
  • High blood sugar
  • Skin reactions at the treated site. Tell your doctor if you get any skin reactions or skin infections.
  • Effects on growth and weight in children

Vision problems: May increase your chance of developing cataract(s) and glaucoma. Tell your healthcare provider if you develop blurred vision or other vision problems during treatment with BRYHALI Lotion.

Is BRYHALI Lotion safe for children?

BRYHALI Lotion has not been tested in patients younger than 18. Children exposed to corticosteroids are at greater risk for endocrine dysfunction.

How long can I use BRYHALI Lotion?

BRYHALI Lotion has safety established for as-needed use for up to 8 weeks. This may be longer than other corticosteroids you have been prescribed before. Talk to your healthcare provider if your skin does not improve after 8 weeks of treatment.

Does BRYHALI Lotion cause the skin to thin?

In clinical trials, BRYHALI Lotion did not cause skin thinning in any patients.

However, since BRYHALI Lotion's active ingredient is a corticosteroid, it may cause thinning of skin (atrophy), stretch marks (striae), spider veins (telangiectasia),
lightened skin (hypopigmentation) and rash (allergic contact dermatitis). Some local adverse reactions may be irreversible.

HOW TO USE
How many times a day do I have to apply BRYHALI Lotion?

BRYHALI Lotion is applied once a day.

How much can I use?

Your doctor will tell you how much to apply per day for your condition. You should not use more than 50 grams in one week.